n.

1. 悲痛，悲傷[U]
   The mother went mad with grief after the child died.

   孩子死後，母親因悲痛而發瘋了。

2. 悲痛的緣由[C]
   Her heroin-addicted husband is a grief to her.

   她那吸海洛因成癮的丈夫真讓她痛心。

3. 不幸；災難；失敗[U][C]

n.

1. intense sorrow, especially caused by someone's death.
   ▸an instance or cause of intense sorrow.
2. informal trouble or annoyance.