differ from

1. 與……不同
   Chinese differs greatly from English in spelling.

   漢語和英語在拼寫上大不相同。

2. 與……意見不合
   We differ from them on the issue.

   我們在這個問題上與他們意見不合。

differ with

1. 與……意見不合
   I differ with her on the matter.

   在這件事上我與她意見不合。

• agree to differ
  amicably stop arguing because agreement will never be reached.
• beg to differ
  politely disagree.