/
ˈkɒlə/
n.
  - (in medieval science and medicine) one of the four bodily humours, identified with bile, believed to be associated with a peevish or irascible temperament.
 - archaic anger or irascibility.
 
Etymology
ME: from OFr. colere, from L. cholera ‘diarrhoea’ (from Gk kholera), which in late L. acquired the senses ‘bile or anger’, from Gk kholē ‘bile’.